Baseline examination: 1990-1991
Follow-up 1: 1994-1995
Follow-up 2: 1997-1998
Follow-up 3: 1999-2000
Baseline: 603 participants
Follow-up 1: 429 participants
Follow-up 2: 301 participants
Follow-up 3: 201 participants
Sociodemographic, health, BP and cognitive data was collected by a nurse. Blood pressure was measured at home with the subject sitting after at least 30 min rest. Presence or absence of specific diseases and medication use was enquired about directly from subjects and from primary care casenotes.
Medical casenotes of the original 603 subjects were sought and then scrutinized at their doctors’ offices. Of these, 429 were available for testing, 69 had died, 15 were too unwell to be tested, 12 had moved from the area, and 78 others either refused retesting or failed to reply to follow-up letters. From the 429 subjects visited by the research nurse at home for a second time, detailed inquiries were made about health and medications.
Repeat measures of blood pressure were taken and more extensive psychometric testing than at baseline were done. n=301
Previous assessments were repeated, but in addition more extensive socioenvironmental, physiological and disability data were collected. n=201 (72 males, 129 females, mean age 83.4 years, SD 3.6 years) participants.
Questionnaires, physical measures, administrative databases
Others: Primary care records
Relationship between blood pressure and cognition
The main aim of the study was to estimate the relationship between blood pressure and cognition.
University of Edinburgh
Alzheimer Scotland Dementia Research Centre
MD. John Starr
Dr. Sally Macintyre
Prof. Dr. Lawrence Whalley
Starr JM, Deary IJ, Macintyre S. Associations with successful ageing in the Healthy Old People in Edinburgh cohort: being well, fit and healthy. Aging Clinical & Experimental Research 2003;15:336-342.