The first follow-up assessments took place approximately 24 months after the first examination and the second after 48 months.
Baseline: 1.321 participants
Follow-up 1: 1.113 participants
Follow-up 2: 1.014
Each participant underwent a comprehensive clinical evaluation that incorporated social, medical and psychological examinations. All assessments were carried out at the Golgi Cenci Foundation with the exception of examinations of participants with significant health problems, which took place at their homes.
The assessments included blood sampling, a social questionnaire, an evaluation of walking speed, a medical examination and a neurological assessment of mood and cognitive functions.
Questionnaires, cognitive measures, physical measures, biosamples (Blood)
Dementia and other mild cognitive impairments
Protective vs. Risk factors
The goals of the InveCe.Ab study are:
To estimate the prevalence and incidence of dementia and its subtypes, mild cognitive impairment, and cognitive impairment with no dementia in people 70 to 74 years of age at baseline.
To investigate the potential risk or protective value of various epidemiologic, clinical, and biological factors as determinants of the quality of cognitive aging and dementia onset. Special attention is given to understanding how modifiable risk factors impact cognitive impairment with and without dementia.
Golgi Cenci Foundation
Dr. Daniele Zaccaria
Guaita A, Colombo M, Vaccaro R, et al. Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the “Invece.Ab” population-based study. BMC Geriatrics, 2013; 13: 98-106.